CIRCULATING TUMOUR CELLS INDICATE THE PRESENCE OF RESIDUAL DISEASE POST-CASTRATION IN PROSTATE CANCER PATIENT-DERIVED XENOGRAFT MODELS

Castrate-resistant prostate cancer (CRPC) is the hdw1620dnpk lethal form of prostate cancer.Epithelial mesenchymal plasticity (EMP) has been associated with disease progression to CRPC, and prostate cancer therapies targeting the androgen signalling axis, including androgen deprivation therapy (ADT), promote EMP.We explored effects of castration on

Abstract Multi-stable structures attract great interest because they possess special energy landscapes with domains of attraction around the stable states.Consequently, multi-stable structures have the potential to achieve prescribed reconfiguration with only a few lightweight actuators (such as shape-memory alloy springs), and do not need constant